腹腔镜胆囊切除术治疗急性胆囊炎的临床效果

Clinical effect of laparoscopic cholecystectomy for acute cholecystitis

目的探讨腹腔镜胆囊切除术治疗急性胆囊炎(AC)的临床效果。方法选取2017年6月~2018年6月我院收治的52例AC患者为研究对象,按随机数字表法分为两组,各26例。对照组行传统开腹胆囊切除术,试验组接受腹腔镜胆囊切除术。比较两组免疫功能指标,围术期指标,血清脂肪酶(LPS)、血清淀粉酶(AMY)和血清碱性磷酸酶(ALP)水平。结果术后试验组CD3^+、CD4^+、CD4^+/CD8^+水平高于对照组,差异有统计学意义(P<0.05),术后试验组围术期指标手术切口小于对照组,手术时间、腹腔引流时间短于对照组,手术出血量少于对照组,差异均有统计学意义(P<0.05),试验组LPS、AMY、ALP水平低于对照组,差异均有统计学意义(P<0.05)。结论腹腔镜胆囊切除术治疗AC效果好,可有效缓解术后免疫功能抑制,降低LPS、AMY、ALP水平,促进患者恢复。

Objective To study the clinical effect of laparoscopic cholecystectomy in the treatment of acute cholecystitis(AC).Methods A total of 52 patients with AC treated in our hospital from June 2017 to June 2018 were selected as study subjects.The patients were randomly divided into two groups according to the random number table method,each had 26 cases.Patients in the control group underwent open cholecystectomy,patients in the experimental group underwent laparoscopic cholecystectomy.The immune function indexes,perioperative indexes,serum lipase(LPS),serum amylase(AMY),and serum alkaline phosphatase(ALP)levels between the two groups were compared.Results Tn the postoperative,the levels of CD3^+,CD4^+,CD4^+/CD8^+experimental group were higher than those in the control group,and the differences were statistically significant(P<0.05).The perioperative index of the experimental group in the postoperative group was less than that of the control group,the operation time and abdominal drainage time were shorter than those in the control group,and the amount of surgical bleeding was less than that in the control group,the differences were statistically significant(P<0.05),The levels of LPS,AMY,and ALP in the experimental group were lower than those in the control group,and the differences were statistically significant(P<0.05).Conclusions Laparoscopic cholecystectomy is effective in treating AC,and can effectively alleviate postoperative immune function suppression,reduce LPS,AMY,ALP and promote patient recovery.