未成熟血小板比率在异基因造血干细胞移植预测血小板植入中的价值

Prediction of platelet implantation by immature platelet ratio in allogeneic stem cell transplantation

目的研究未成熟血小板比率(IPF)指标预测异基因造血干细胞移植(allo-SCT)治疗时血小板(PLT)植入成功的意义。方法检测35例allo-SCT患者外周血PLT、IPF及未成熟血小板绝对值(A-IPF),采用这3项指标预测allo-SCT治疗时PLT植入成功的时间。结果 IPF判断移植患者PLT植入的时间比PLT提前1-3d,A-IPF可以起到很好的补充作用。结论 IPF和A-IPF可更早预测PLT植入时间,可作为临床评价alloSCT后PLT植入新的指标。

Objective To study the prediction role of immature platelet ratio(IPF) for platelet(PLT) implantation during allogeneic stem cell transplantation(allo-SCT). Methods A total of 35 allo-SCT cases were enrolled. The PLT count,IPF and the absolute value of immature platelet(A-IPF) in peripheral blood were determined. These parameters were used to predict the success time of PLT implantation during allo-SCT. Results IPF was 1-3 d earlier than PLT count in predicting PLT implantation,and A-IPF could play a good complementary role. Conclusions IPF and A-IPF can predict the time of PLT implantation earlier,which can be used as new parameters for the clinical evaluation of PLT implantation after allo-SCT.