超声内镜引导下细针抽吸活检对胰腺占位性病变的诊断效果的影响因素

Influencing factors of diagnostic efficacy of endoscopic ultrasound-guided fine needle aspiration biopsy for pancreatic space-occupying lesions

目的探讨超声内镜引导下细针抽吸活检(EUS-FNA)对胰腺占位性病变的诊断效果的影响因素。方法回顾性分析86例因影像学检查发现胰腺占位性病变行EUS-FNA检查患者的临床资料。根据细胞学或病理学结果评价EUS-FNA的诊断效果。采用Logistic回归模型分析EUS-FNA诊断效果的影响因素。结果86例患者中,65例患者经EUS-FNA明确诊断。Logistic多因素分析结果显示,病灶大小、胰管或胆总管扩张情况是EUS-FNA对胰腺占位性病变的诊断效果的影响因素(均P<0.05)。结论EUS-FNA对胰腺占位性病变的诊断效果可能受病灶大小、有无胰管或胆总管扩张的影响。

Objective To explore the influencing factors of diagnostic efficacy of endoscopic ultrasound-guided fine-needle aspiration(EUS-FNA)biopsy for pancreatic space-occupying lesions.Methods The clinical data of 86 patients with pancreatic space-occupying lesions diagnosed by imaging examination,who underwent EUS-FNA examination,were analyzed retrospectively.The diagnostic efficacy of EUS-FNA was assessed based on cytological or pathological results.Logistic regression model was used to analyze the influencing factors of diagnosis efficacy of EUS-FNA.Results Among the 86 patients,65 patients obtained definite diagnosis by EUS-FNA.Logistic multivariate analysis results showed that focus size,presence or absence of pancreatic duct or common bile duct dilatation were the influencing factors of diagnostic efficacy of EUS-FNA for pancreatic space-occupying lesions(all P<0.05).Conclusion The diagnostic efficacy of EUS-FNA for pancreatic space-occupying lesions may be affected by focus size,presence or absence of pancreatic duct or common bile duct dilatation.