从不同维度识别及验证成人急性白血病病人化疗期间症状群

Identifying and confirming symptom clusters from different dimensions in adult acute leukemia receiving chemotherapy

[目的]从症状的不同维度识别及验证成人急性白血病病人化疗期间的症状群,为症状群的正确识别提供理论参考。[方法]选取198例成人急性白血病化疗病人,采用记忆症状评估量表中文版(MSAS-ch)从症状的发生、严重、困扰3个维度进行评估,探索性因子分析识别症状群,验证性因子分析检测症状群的可靠性。[结果]严重维度识别症状群的可接受性优于发生和困扰维度,从严重维度共识别5个症状群:心理症状群、恶心-呕吐症状群、能量不足症状群、食欲缺乏-食物味道改变症状群、疼痛-冒汗症状群。[结论]医务人员可从症状严重维度识别病人的症状群,为症状群的正确识别及干预措施的制定提供理论依据。

Objective:To identify and confirm symptom clusters(SCs)of acute leukemia(AL)from different dimensions,and provide theoretical references for correct recognition of symptom clusters.Methods:A total of 198 patients with AL undergoing chemotherapy were selected in the study.The Chinese version of the Memory Symptom Assessment Scale(MSAS-CH)was used to evaluate the occurrence,severity and distress of symptoms.Exploratory factor analysis was used to identify the SCs,and confirmatory factor analysis was used to detect the reliability of the SCs.Results:The acceptability of severe dimension was better than that of occurrence and distress dimension,and five SCs were recognized from the severe dimension:psychological symptom clusters,nausea-vomiting symptom clusters,energy deficiency symptom clusters,anorexia-food taste change symptom clusters,and pain-sweating symptom clusters.Conclusions:Medical staff can identify SCs from the severity of symptoms,and lay a theoretical basis for the correct identification of SCs and the development of intervention measures.