研究探讨在冠心病快速心律失常患者治疗中采用胺碘酮的临床治疗效果

To Investigate the Clinical Effect of Amiodarone in the Treatment of Patients with Tachyarrhythmia of Coronary Heart Disease

目的探讨将胺碘酮应用于冠心病快速心律失常患者治疗中的临床治疗效果。方法抽取本院2017年1月至2018年7月收纳的冠心病快速心律失常患者136例进行本次研究,利用区组随机化分组法将其分为传统治疗组与胺碘酮治疗组,每组各有患者68例,且其一般资料对比无明显差异(P> 0.05)。两组均进行常规治疗,在此基础上传统治疗组患者采用传统药物进行治疗,胺碘酮治疗组则在常规治疗基础上行胺碘酮治疗,对比分析两组患者不良反应发生情况及治疗效果情况。结果胺碘酮治疗组不良反应发生率(1例恶心,1例呕吐,1例乏力)及治疗有效率分别为4.4%、91.2%,传统治疗组不良反应发生率(4例恶心,3例呕吐,3例乏力)及治疗有效率分别为14.7%、73.5%,统治疗组不良反应发生率及治疗有效率明显优于传统治疗组,且差异具有统计学意义(P <0.05)。结论在冠心病快速心律失常患者的治疗中,运用胺碘酮进行治疗可有效提高患者治疗有效率,降低不良反应发生率,可在此类患者的临床治疗大力推广运用。

Objective To investigate the clinical effect of amiodarone in the treatment of patients with coronary heart disease(cad) with tachyarrhythmia. Methods A total of 136 patients with tachyarrhythmia of coronary heart disease admitted in our hospital from January 2017 to July 2018 were selected for this study. They were divided into conventional treatment group and amiodarone treatment group by regional randomized grouping method. There were 68 patients in each group, and there was no significant difference in general data(P>0.05). Conventional treatment was performed in both groups. On this basis, patients in the traditional treatment group were treated with traditional drugs, while patients in the amiodarone treatment group were treated with amiodarone on the basis of conventional treatment. Adverse reactions and therapeutic effects of the two groups were compared and analyzed. Results The incidence of amiodarone treatment group adverse reactions(1 case was 1 case of nausea, vomiting, cases of lack of power) and the treatment efficient don’t 4.4%, 91.2%, the incidence of traditional treatment group adverse reactions(4 cases of nausea, 3 cases of vomiting, 3 cases of lack of power) and the treatment effectiveness were 14.7%, 73.5%, incidence of adverse reactions and the treatment efficient system treatment group was obviously better than the traditional treatment group, and the difference is statistically significant(P<0.05). Conclusion Amiodarone can effectively improve the treatment efficiency and reduce the incidence of adverse reactions in the treatment of patients with coronary heart disease with tachyarrhythmia, and it can be widely used in the clinical treatment of such patients.