摘要
目的:研究核磁共振成像(MRI)与良性前列腺增生(BPH)组织学成分的关系。方法:选取43例前列腺穿刺患者(均确认为BPH),穿刺前行核磁共振检查。穿刺标本进行腺体百分比测算,并记录各穿刺点的影像学信号强度,进行差异性分析。利用IMAGE J软件对MRI图像进行分析,判断腺体成分比,并与前列腺体积(TPV)、前列腺特异性抗原(PSA)、国际前列腺症状评分(IPSS)、残余尿量(RUV)等临床数据进行相关性分析。结果:腺瘤组、混合组、间质组在穿刺点/外周带信号比上存在显著性差异,提示腺体成分表现出较高的信号比而间质成分信号比较低。影像学图片中腺体成分比与PSA、TPV存在正相关性,与IPSS评分和RUV无明显相关性。结论:通过MRI检查,可以在临床上通过无创的方法,来判断增生部分的腺体比例,为治疗用药和决策提供帮助。
Objective:To study the predictive value of magnetic resonance imaging(MRI)signal intensity on benign prostatic hyperplasia(BPH)histological features.Method:Forty-three patients who accepted prostatic biopsy were recruited in this study.All these patients were confirmed as BPH by pathological examination.MRI was introduced before biopsy,and the signal intensity of transitional zone/peripheral zone were recorded as a parameter to be compared within 3pathological groups(adenomatous,interstitial,mixed).The area ratio of adenomatous components were calculated with IMAGE J software to detect the relevance of clinical data such as prostatic specific antigen(PSA),total prostate volume(TPV),International Prostatic Symptom Score(IPSS),residual urine volume(RUV).Result:There are significant differences in signal intensity of transitional zone/peripheral zone within 3pathological groups.High signal intensity represented abundant adenomatous tissue.The area ratios of adenomatous components were related to PSA and TPV,but not to IPSS and RUV.Conclusion:MRI,a non-invasive and useful tool to predict the pathological component of BPH,would be of benefit to medication and treatment strategy.
作者
康健
管雯斌
朱自强
李晓明
周硕明
徐丁
段刘剑
齐隽
KANG Jian;GUAN Wenbin;ZHU Ziqiang;LI Xiaoming;ZHOU Shuoming;XU Ding;DUAN Liujian;QI JUN(Department of Urology,Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine,Shanghai,200092,China;Department of Pathology,Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine;Department of Radiology,Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine)
出处
《临床泌尿外科杂志》
2020年第5期367-370,共4页
Journal of Clinical Urology