头罩无创通气联合沙丁胺醇对急性呼吸衰竭患者血气交换及氧合指数的影响

Effect of head mask noninvasive ventilation combined with salbutamol on blood gas exchange and oxygenation index in patients with acute respiratory failure

目的探讨头罩无创通气联合沙丁胺醇在急性呼吸衰竭患者中的应用效果。方法回顾性分析2018年9月至2019年8月于本院接受治疗的60例急性呼吸衰竭患者的临床资料,根据治疗方式的不同分为对照组(n=30,头罩无创通气)和观察组(n=30,头罩无创通气联合沙丁胺醇),比较两组血气交换[肺泡动脉氧分压差P(A-a)O2]、氧合指数(OI)、不良反应发生率。结果治疗后,观察组P(A-a)O2值低于对照组,OI值高于对照组,差异有统计学意义(P<0.05);两组不良反应发生率比较差异无统计学意义。结论头罩无创通气联合沙丁胺醇治疗可改善急性呼吸衰竭患者血气交换及氧合指数,同时可控制不良反应发生。

Objective To investigate the effect of head mask noninvasive ventilation combined with salbutamol in patients with acute respiratory failure.Methods The clinical data of 60 patients with acute respiratory failure treated in our hospital from September 2018 to August 2019 were retrospectively analyzed,and they were divided into control group(n=30,head mask noninvasive ventilation)and observation group(n=30,head mask noninvasive ventilation combined with salbutamol)according to the different treatment methods.Blood gas exchange[alveolar arterial oxygen pressure difference P(A-a)O2],oxygenation index(OI),adverse events were compared between the two groups.Results After treatment,the P(A-a)O2 value of the observation group was lower than that of the control group,and the OI value was higher than that of the control group,the difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse events between the two groups.Conclusion Head mask noninvasive ventilation combined with salbutamol can improve blood gas exchange and oxygenation index in patients with acute respiratory failure and control the occurrence of adverse events.