湘潭县和融水县2岁以下婴幼儿轮状病毒腹泻病流行病学调查

Epidemiological investigation on rotavirus diarrhea in infants at ages of less than 2 years in Xiangtan County, Hunan Province and Rongshui County, Guangxi Zhaung Autonomous Region,China

目的通过对监控区域内腹泻病例的监测,获取轮状病毒(rotavirus,RV)腹泻发生率。方法在广西壮族自治区融水县、湖南省湘潭县两个地区的村卫生室及乡镇卫生院中开展腹泻监测,收集腹泻病例和流行病学信息,采集病例粪便样本。应用ELISA法检测RV,RT-PCR法对其进行基因分型。结果湘潭县和融水县RV腹泻高峰主要集中在2月份,分别占总数的45.9%和53.9%;两地腹泻发病率为285.1/(1000人·年),RV检出率为18.0%,RV腹泻发病率为51.2/(1000人·年);湘潭县和融水县的轮状病毒血清型均以G9型(分别占58.7%和73.7%)和P8型为主(分别占67%和81.6%)。结论RV是导致2岁以下婴幼儿腹泻的常见病原体,湘潭和融水县的RV流行株均为G9型和P8型,流行高峰为2月。

Objective To obtain the incidence of rotavirus(RV)diarrhea by monitoring the cases of diarrhea in Xiangtan County,Hunan Province and Rongshui County,Guangxi Zhaung Autonomous Region,China.Methods Diarrhea monitoring was carried out in clinics and town hospitals in Xiangtan and Rongshui Counties,and the diarrhea cases and epidemiological data were collected.The fecal samples were tested for RV by ELISA,and subjected to genotyping by RTPCR.Results The peak of RV diarrhea in Xiangtan and Rongshui appeared in February,which accounting for 45.9%and 53.9%of total cases respectively.The total incidence of diarrhea in the two counties was 285.1/(1000 person·year),while the detection rate of RV was 18.0%,and the incidence rate of RV diarrhea was 51.2/(1000 person·year).Both the predominant serotypes of RV in Xiangtan and Rongshui were G9(58.7%and 73.7%respectively)and P8(67%and81.6%respectively).Conclusion RV is a common pathogen of diarrhea in infants at ages of less than 2 years.The epidemic RV strains in Xiangtan and Rongshui counties were of serotypes G9 and P8,and the peak of epidemic appeared in February.