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急性白血病合并HIV感染五例临床分析

Clinical analysis in five patients with acute leukemia and HIV infection
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摘要 人类免疫缺陷病毒(HIV)感染患者可以出现多种血液系统异常。随着高效抗逆转录病毒治疗(HAART)的进步,HIV患者生存期延长,合并霍奇金淋巴瘤、骨髓增生异常综合征、急性白血病、纯红细胞再生障碍等也有报道。其中,急性白血病虽然罕见,但在HIV患者中发病率高于正常人群[1,2]。2004、2014年我国分别报道HIV感染合并急性髓系白血病(AML)M4型[3]和M2型[4]各1例,2013、2018年报道HIV感染合并急性淋巴细胞白血病(ALL)L3型[5]和L2型[6]各1例。这4例患者均未能接受白血病治疗,短期内死亡。可见,对于急性白血病合并HIV感染的诊治认识还很不足。本研究报道5例急性白血病合并HIV感染患者的临床特征、诊治及结局。
作者 王珞 张炎 王为 张路 杨辰 庄俊玲 韩冰 周道斌 陈苗 Wang Luo;Zhang Yan;Wang Wei;Zhang Lu;Yang Chen;Zhuang Junling;Han Bing;Zhou Daobin;Chen Miao(Department of Internal Medicine,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,China;Department of Hematology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,China)
出处 《中华血液学杂志》 CAS CSCD 北大核心 2020年第6期517-520,共4页 Chinese Journal of Hematology
基金 国家自然科学基金(81970106)。
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