心理护理在阿昔洛韦联合胸腺肽治疗生殖器疱疹中的应用及对患者不良反应发生的影响

Psychological nursing for genital herpes patients receiving acyclovir plus thymosin and its effect on the incidence of adverse reactions

目的:探究心理护理在阿昔洛韦联合胸腺肽治疗生殖器疱疹中的应用及对患者不良反应发生的影响。方法:选取2016年1月至2018年12月收治的生殖器疱疹患者160例,随机分为对照组和研究组,各80例。两组患者均服用阿昔洛韦片和胸腺肽肠溶片治疗,对照组采用常规护理,研究组采用心理护理。以焦虑自评量表(SAS)和抑郁自评量表(SDS)对患者进行焦虑、抑郁的评定,比较两组患者护理干预前后焦虑和抑郁情况、不良反应发生情况以及满意度。结果:护理干预后,研究组患者焦虑SAS评分[(39.05±2.97)分vs(45.71±3.36)分]、抑郁SDS评分[(41.74±2.86)分vs(47.28±3.95)分]均显著低于对照组(P均<0.01);研究组患者不良反应发生率显著低于对照组(22.50%vs 47.50%,P<0.05);研究组患者护理满意度显著高于对照组(95.00%vs 77.5%,P<0.01)。结论:通过心理护理,能够减少阿昔洛韦联合胸腺肽治疗的生殖器疱疹患者不良反应的发生,改善患者的心理状态,减少焦虑和抑郁情绪。

Objective: To explore the application of psychological nursing in patients with genital herpes receiving acyclovir combined with thymosin and its effect on the incidence of adverse reactions. Methods: A total of 160 patients with genital herpes treated with acyclovir plus thymosin in our hospital from January 2016 to December 2018 were randomly allocated to receive conventional nursing(the control group, n = 80) and psychological nursing(the trial group, n = 80). Self-rating Anxiety Scale(SAS) and Self-rating Depression Scale(SDS) were used to evaluate the anxiety and depression of the patients, and comparisons were made between the two groups of patients in their SAS and SDS scores, the incidence of adverse reactions and their satisfaction with nursing intervention. Results: After nursing intervention, the patients of the trial group, compared with the controls, showed significantly lower SAS scores(39.05 ± 2.97 vs 45.71 ± 3.36, P < 0.01), SDS scores(41.74 ± 2.86 vs 47.28 ± 3.95, P < 0.01), and incidence of adverse reactions(22.50% vs 47.50%, P < 0.05), but a markedly higher rate of satisfaction with nursing intervention(95.00% vs 77.5%, P < 0.01). Conclusion: Psychological nursing can reduce the incidence of adverse reactions in genital herpes patients receiving acyclovir combined with thymosin and meanwhile improve the mental status of the patients by alleviating their anxiety and depression.