摘要
支气管哮喘(哮喘)是威胁公共健康最常见的慢性肺部炎症性疾病之一,是一种由基因与环境相互作用驱动的异质性疾病。"卫生假说"与"微生物假说"的提出,使人们逐渐注意到微生物与哮喘之间的密切联系。近年来有关肠道菌群的研究层出不穷,研究表明,肠道菌群不仅与消化、免疫、内分泌、循环、神经精神系统有着千丝万缕的关系,更是与哮喘存在着一定的相关性。该文从肠道菌群的生理作用出发,探讨肠道菌群与儿童哮喘之间的联系,从而发掘哮喘未来的防治策略。
Asthma is one of the most common pulmonary chronic inflammatory diseases threatening public health.It is a heterogeneous disease driven by gene-environment interaction.The proposition of"hygiene hypothesis"and"microbial hypothesis"has gradually drawn attention to the close relationship between microorganisms and asthma.In recent years,studies on intestinal flora emerge endlessly.Studies have shown that intestinal flora is not only closely related to digestion,immunity,endocrine,circulation,neuropsychiatric system,but also to asthma.This paper reviews the possible relationship between intestinal flora and asthma in children from its physiological function,so as to explore the prevention and treatment strategy of asthma in the future.
作者
鲁婷婷(综述)
邹映雪(审校)
Lu Tingting;Zou Yingxue(Graduate School of Tianjin Medical University,Tianjin 300070,China;The Second Respiratory Department and Infection Department of Tianjin Children′s Hospital,Tianjin 300134,China)
出处
《国际儿科学杂志》
2020年第6期389-393,共5页
International Journal of Pediatrics
