右美托咪啶在超声引导下腹横筋膜阻滞对剖宫产术后镇痛的效果观察

Observation of the Effect of Dexmedetomidine on Ultrasound-guided Abdominal Fascia Block on Analgesia after Cesarean Section

目的:探讨在进行超声引导下腹横筋膜阻滞时使用右美托咪啶对剖宫产术后镇痛的效果。方法:选择68例剖宫产的患者,根据不同的右美托咪啶剂量随机分为四组,17例一组,Ⅰ组为不使用右美托咪啶,Ⅱ组为右美托咪啶剂量0.25μg/(kg·h),Ⅲ组为右美托咪啶剂量0.5μg/(kg·h),Ⅳ组为右美托咪啶剂量0.75μg/(kg·h),分析四组的麻醉前后VAS疼痛评分,血压和心率变化。结果:右美托咪啶剂量0.5μg/(kg·h)的VAS评分明显优于其它三组(P<0.05),使用右美托咪啶的三组血压和心率变化优于Ⅰ组(P<0.05)。结论:在进行超声引导下腹横筋膜阻滞时使用右美托咪啶0.5μg/(kg·h)的剂量对剖宫产术后镇痛具有明显效果,VAS评分较低,并不会引起血压和心率的变化,因此可在临床推广应用。

Objective: To explore the effect of using dexmedetomidine on analgesia after cesarean section under abdominal ultrasound-guided transverse fascia block. Methods: From April 2018 to April 2019, 68 patients with cesarean section were randomly divided into 4 groups according to different doses of dexmedetomidine, a group of 17 cases, group Ⅰ was not using dexmedetom Mimididine, group Ⅱ is dexmedetomidine dose 0.25μg/(kg·h), group Ⅲ is dexmedetomidine dose 0.5μg/(kg·h), group Ⅳ is dexmedetomidine dose 0.75μg/(kg·h), analyze the changes of VAS pain score, blood pressure and heart rate before and after anesthesia in 4 groups. Results: The VAS score of dexmedetomidine at a dose of 0.5μg/(kg·h)was significantly better than that of the other 3 groups(P<0.05), and the changes in blood pressure and heart rate of the 3 groups using dexmedetomidine were better than the Ⅰ group(P<0.05). Conclusion: The use of dexmedetomidine 0.5μg/(kg·h)in the ultrasound-guided abdominal transverse fascia block has a significant effect on analgesia after cesarean section. The VAS score is low and does not cause blood pressure. And heart rate changes, so it can be used in clinical promotion.