肠易激综合征体质与焦虑抑郁相关分析

Discussion on the Relationship between Constitution of Irritable Bowel Syndrome and Anxiety-Depression

目的:探讨肠易激综合征(irritable bowel syndrome,IBS)体质与焦虑抑郁的相关性。方法:选择2018年5月至2019年4月在上海市青浦区朱家角人民医院(98例)和复旦大学附属中山医院青浦分院(66例)接受治疗的IBS患者进行研究。采用现场问卷调查的方法进行研究,调查工具包括:自制一般情况调查表、中医9种基本体质分类量表、焦虑自评量表(self-rating anxiety scale,SAS)和抑郁自评量表(self-rating depression scale,SDS)。对比不同焦虑、抑郁患者体质分布情况,并进行相关性分析。结果:本次调查共发放问卷164份,回收有效问卷162份,回收有效率为98.78%。无焦虑抑郁患者体质以平和质(65.22%)为主,焦虑患者以阳虚质(29.82%)与气虚质(28.07%)为主,抑郁患者以气郁质(62.50%)为主,焦虑、抑郁患者以气郁质(66.67%)为主,不同心理状况IBS患者体质分布情况对比差异具有统计学意义(P<0.05)。不同程度焦虑IBS患者体质分布差异有统计学意义,重度焦虑患者阳虚质、气虚质比例明显高于轻度与中度焦虑者(P<0.05),相关性分析结果显示:IBS患者焦虑程度与阳虚质、气虚质分布率呈显著正相关关系(r=0.710, 0.518,P<0.05)。不同抑郁程度IBS患者体质分布差异有统计学意义,重度抑郁患者气郁质明显高于轻度及中度抑郁者,相关性分析结果显示:IBS患者抑郁程度与气郁质分布率呈显著正相关关系(r=0.692,P<0.05)。结论:肠易激综合征患者体质与焦虑、抑郁具有显著相关性,阳虚质、气虚质患者焦虑发生率更高,气郁质患者抑郁发生率更高。

Objective:To investigate the relationship between constitution of irritable bowel syndrome(IBS and anxiety-depression.Methods:From May 2018 to April 2019,98 patients with IBS who were treated in Zhujiajiao People’s Hospital in Qingpu District and 66 in Qingpu Branch of Zhongshan Hospital Affiliated to Fudan University were selected for the study.This study was conducted by means of on-site questionnaires,including self-made general situation questionnaire,9 basic constitution classification scales of traditional Chinese medicine,self-rating anxiety scale(SAS)and self-rating depression scale(SDS).Then the author compared the physical distribution of different anxiety and depression patients,and analyzed the correlation.Results:A total of 164 questionnaires were distributed in this survey,and 162 valid questionnaires were collected.The recovery efficiency was 98.78%.The constitution of patients without anxiety and depression was mainly composed of gentleness type(65.22%).The main constitution of anxiety patients were Yang deficiency type(29.82%)and Qi deficiency type(28.07%).The main constitution of depression patients was Qi stagnation type(62.50%).The main constitution of anxiety-depression patients was Qi stagnation type(66.67%).There was statistical significance in the distribution of IBS patients with different psychological conditions(P<0.05).There was a statistically significant difference in the distribution of physique between patients with different degrees of anxiety in IBS.The proportion of Yang deficiency and Qi deficiency in patients with severe anxiety was significantly higher than that in patients with mild to moderate anxiety(P<0.05).The results of correlation analysis showed that there was a significant positive correlation between anxiety and the distribution rate of Yang deficiency type and Qi deficiency type(r=0.710,0.518,P<0.05).There was significant difference in the physical distribution of IBS patients with different depression levels.The Qi stagnation type of patients with severe depression was significantly higher than that of patients with mild and moderate depression.The results of correlation analysis showed that there was a significant positive correlation between the anxiety level of IBS patients and the Qi stagnation type distribution rate(r=0.692,P<0.05).Conclusion:The constitution of patients with irritable bowel syndrome is significantly correlated with anxiety and depression.The incidence of anxiety in patients with Yang deficiency and Qi deficiency is higher,and the incidence of depression in patients with Qi stagnation is higher.