脑转移瘤原发灶来源判别的MRI研究进展

Progress of MRI in identifying the origin of brain metastases

脑转移瘤是成人最常见的中枢神经系统肿瘤,明确原发肿瘤来源对病人的临床决策及治疗预后至关重要。随着磁共振波谱成像、扩散加权成像、扩散张量成像、MR灌注成像、磁敏感加权成像等功能MRI的不断完善以及影像组学的发展,可以提供脑转移瘤的生理、代谢以及影像特征信息,提高了对原发恶性肿瘤来源或病理类型判别的诊断准确性。就功能MRI和影像组学判别脑转移瘤原发灶来源的应用进展予以综述。

Brain metastases are the most common central nervous system tumors in adults, and clarifying the origin of the primary tumor is critical to the patient’s clinical decision and prognosis. With the continuous improvement of functional MRI such as MR spectroscopy, diffusion weighted imaging, diffusion tensor imaging, MR perfusion imaging,susceptibility weighted imaging, as well as the development of radiomics, it can provide physiological, metabolic and imaging characteristics information of brain metastases, and consequently can improve the accuracy of diagnosis of the origin or pathological type of primary malignant tumors. This article reviews the application progress of functional MRI and radiomics in identifying the origin of brain metastases.