脑血管病及血管性危险因素与血管性认知功能损害的关系研究

Study on correlation between cerebrovascular disease,vascular risk factors and vascular cognitive impairment

目的分析脑血管病及血管性危险因素与血管性认知功能损害的关系。方法60例脑血管病患者,以是否存在血管性认知功能损害为准分为对照组(无血管性认知功能损害)和研究组(存在血管性认知功能损害),各30例。回顾性分析并对比两组患者年龄分布情况、脑血管病面积、损伤半球情况及脑血管损伤部位。结果研究组70~79岁患者占比56.67%高于对照组的30.00%,差异有统计学意义(P<0.05)。研究组一般损伤患者占比低于对照组,腔隙性损伤、大面积损伤患者占比高于对照组,差异有统计学意义(P<0.05)。研究组双侧半球损伤患者占比70.00%高于对照组的43.33%,差异有统计学意义(P<0.05)。研究组基底节损伤发生率70.00%高于对照组的43.33%,差异有统计学意义(P<0.05)。结论对于脑血管病患者,血管性认知功能损害与高龄、大面积损伤、双侧半球损伤、基底节损伤等因素相关,这些因素均为血管性危险因素,应予以重视,避免血管性认知功能损害的发生。

Objective To analyze the correlation between cerebrovascular disease,vascular risk factors and vascular cognitive impairment.Methods A total of 60 cerebrovascular disease patients were divided into control group(without vascular cognitive impairment)and research group(with vascular cognitive impairment)according to whether there was vascular cognitive impairment,with 30 cases in each group.The age distribution,the area of cerebrovascular disease,the condition of damaged hemisphere and the location of cerebrovascular injury were compared between the two groups.Results Proportion of 70-79 years old patients in the research group 56.67%was higher than that of the control group 30.00%,and the difference was statistically significant(P<0.05).The proportion of patients with general injury in the research group was lower than that in the control group,and the proportion of patients with lacunar injury and large-area injuries was higher than that in the control group,and the difference was statistically significant(P<0.05).The proportion of patients with bilateral hemispheric injury 70.00%in the research group was higher than that in the control group 43.33%,and the difference was statistically significant(P<0.05).The incidence of basal ganglia injury 70.00%in the research group was higher than that in the control group 43.33%,and the difference was statistically significant(P<0.05).Conclusion For patients with cerebrovascular disease,vascular cognitive impairment is correlated to factors such as advanced age,large-area injury,bilateral hemispheric injury,and basal ganglia injury.These factors are vascular risk factors and should be taken seriously to avoid vascular cognitive impairment.