化痰丸治疗痰热壅肺型支气管扩张症的临床观察

Clinical observation of Huatan pills in the treatment of bronchiectasis of phlegm-heat obstructing lung type

目的观察院内制剂化痰丸治疗痰热壅肺型支气管扩张症的临床疗效。方法80例痰热壅肺型支气管扩张症患者,随机分为对照组和治疗组,每组40例。对照组采用常规西药治疗,治疗组在常规西药治疗的基础上加用化痰丸治疗。比较两组患者治疗前后的白细胞计数(WBC)、C反应蛋白(CRP)、钙素原(PCT)水平及中医证候积分,临床疗效。结果治疗后,两组患者的WBC、CRP、PCT水平均较本组治疗前降低,且治疗组患者的WBC、PCT水平均低于对照组,差异均具有统计学意义(P<0.05);两组患者治疗后的CRP水平比较,差异无统计学意义(P>0.05)。治疗后,两组患者的中医证候积分均较本组治疗前降低,且治疗组(8.95±2.58)分低于对照组的(12.84±3.12)分,差异均具有统计学意义(P<0.05)。治疗组总有效率为90.0%,高于对照组的72.5%,差异具有统计学意义(P<0.05)。结论化痰丸联合常规西医药治疗痰热壅肺型支气管扩张症效果明显,值得推广使用。

Objective To observe the clinical efficacy of hospital preparation Huatan pills in the treatment of bronchiectasis of phlegm-heat obstructing lung type.Methods A total of 80 patients with bronchiectasis of phlegm-heat obstructing lung type were randomly divided into control group and treatment group,with 40 cases in each group.The control group was treated by conventional Western medicine,and the treatment group was treated by Huatan pills on the basis of conventional Western medicine.The white blood cell(WBC)count,C-reactive protein(CRP),procalcitonin(PCT)levels and traditional Chinese medicine syndrome integral before and after treatment,and clinical efficacy were compared between the two groups.Results After treatment,the levels of WBC,CRP and PCT of the two groups were lower than those before treatment of the same group,and WBC,PCT levels of the treatment group were lower than those of the control group,and the difference was statistically significant(P<0.05).After treatment,there was no statistically significant difference in CRP level between the two groups(P>0.05).After treatment,the traditional Chinese medicine syndrome integral of the two groups were lower than those before treatment of the same group,and the treatment group(8.95±2.58)points was lower than that of the control group(12.84±3.12)points,and the difference was statistically significant(P<0.05).The total effective rate of the treatment group was 90.0%,which was higher than that of the control group 72.5%,and the difference was statistically significant(P<0.05).Conclusion Huatan pills combined with conventional Western medicine shows obviously effect for bronchiectasis of phlegm-heat obstructing lung type,and it is worthy of promotion and application.