腹腔镜下卵巢囊肿剔除术对患者术后炎症因子水平及卵巢功能的影响

Effect of laparoscopic ovarian cystectomy for treating women with ovarian cyst on their postoperative inflammatory factors and ovarian function

目的:分析腹腔镜卵巢囊肿剔除术对患者术后炎症因子水平及卵巢功能的影响。方法:选取2017年2月—2018年12月本院收治的卵巢囊肿患者116例,对照组给予开腹卵巢囊肿剔除术,观察组给予腹腔镜下卵巢囊肿剔除术,比较两种手术效果及激素水平。结果:观察组术中出血量(58.4±12.4ml)少于对照组,胃肠道功能恢复时间(1.6±0.5)d和住院时间(6.0±1.3)d短于对照组,总并发症率(6.7%)少于对照组,术后白细胞介素-6(5.41±0.67)pg/L、肿瘤坏死因子-α(11.02±0.86)pg/ml水平均低于对照组;术后3个月、6个月时雌二醇水平高于对照组,卵泡刺激素和促黄体生成素水平低于对照组;1年内复发率(1.7%)低于对照组,月经恢复正常率(91.4%)高于对照组(均P<0.05)。结论:腹腔镜下卵巢囊肿剔除术创伤小,恢复快,对卵巢功能影响较小且复发率低。

Objective:To analyze the effect of laparoscopic ovarian cystectomy for treating women with ovarian cyst on their postoperative inflammatory factors and ovarian function. Methods: From February 2017 to December 2018, 116 patients with ovarian cyst were selected and divided into two groups. The women in the control group were given open ovarian cyst excision, and the women in the observation group were given laparoscopic ovarian cyst excision. The surgical effects and hormone levels of women were compared between the two groups. Results: The intraoperative bleeding volume, the recovery time of gastrointestinal function, the hospitalization time, the total complication rate, and the levels of interleukin-6 and the tumor necrosis factor-αof women in the observation group were 58.4±12.4 ml, 1.6±0.5 d, 6.0±1.3 d, 6.7%, 5.41±0.67 pg/L, and 11.02±0.86 pg/ml, which were significant less than those of women in the control group. In 3 or 6 months after operation, the level of estradiol of women in the observation group was significant higher than that of women in the control group, but the levels of follicle stimulating hormone and luteinizing hormone of women in the observation group were significant lower. Within one year after operation, the recurrence rate of women in the observation group was 1.7%, which was significant lower than that of women in the control group, but the menstrual recovery rate of women in the observation group was 91.4%, which was significant higher(all P<0.05). Conclusion: Laparoscopic ovarian cystectomy for treating women with ovarian cyst has less trauma, fast recovery, little effect on ovarian function, and low recurrence rate.