阴道环的研究进展

Recent Advances of Vaginal Rings

阴道环(VRs)是缓控释给药系统中的一种剂型。随着VRs技术的不断发展,VRs逐渐被人们接受,在生殖健康领域得到了应用。研究初期VRs主要用于避孕和激素替代疗法,近年来开始将VRs技术应用于辅助生殖、抗人类免疫缺陷病毒(HIV)感染、治疗子宫内膜异位症等。并通过多功能VRs可实现多种药物同时缓释达到多种治疗目的,如使VRs抗HIV感染兼具避孕成为可能。

Vaginal rings is one of the sustained and controlled release drug delivery systems. With the continuous technological development of vaginal rings, they have been accepted widely, especially in reproductive health field. At an early stage, they were mainly used for contraception and hormone replacement therapy. In recent years, they have been generally applied in the field of reproductive health, such as assisted reproductive techniques, anti-HIV infections, and the treatment of endometriosis. Furthermore, vaginal rings make it possible to deliver two or more drugs simultaneously for achieving the multipurpose therapy, such as HIV prevention combined with contraception.