超声检测颈动脉表现特征及血LDH、FA、IL-6水平变化在评估急性脑梗死病情进展中的价值分析

Value analysis of carotid artery manifestations and changes in blood LDH,FA and Il-6 levels in evaluating the progression of acute cerebral infarction by ultrasonography

目的探讨超声检测颈动脉表现特征及血LDH、FA、IL-6水平检测在评估急性脑梗死病情进展中的临床价值分析。方法收集2017年1月-2018年7月间在我院收治的急性脑梗死患者,其中急性脑梗死组(ACI组)106例,对照组为同期在我院非脑梗死患者110例。采集血清乳酸脱氢酶(LDH)、叶酸(FA)、白细胞介素(IL-6)及颈动脉超声检查结果,进行统计学分析。结果ACI组患者血清LDH、FA、IL-6水平分别为(254.56±62.87)U/L、(7.63±4.13)ng/ml、(88.35±13.56)ng/L,血清LDH及IL-6水平高于对照组(P<0.05),血清FA水平低于对照组(P<0.05);超声检测显示ACI组患者斑块发生率及颈动脉狭窄发生率明显高于对照组(P<0.05);ACI组患者颈动脉粥样硬化斑块超声类型以不均质回声斑块最多,发生率高于对照组(P<0.05),低回声斑块发生率高于对照组(P<0.05)。结论与对照组相比,ACI组患者血清LDH、FA、IL-6水平出现异常,颈动脉超声检测显示颈动脉内膜增厚、不光滑,内径减小,斑块形成,表明超声检测颈动脉表现特征和血LDH、FA、IL-6水平检测在急性脑梗死病情评价中具有一定的临床价值。

Objective To explore the clinical value of ultrasonic detection of carotid artery as well as LDH,FA and IL-6 levels in evaluating the progress of acute cerebral infarction.Methods One hundred and six patients with acute cerebral infarction(ACI group)and 110 patients without cerebral infarction in the control group were collected from January 2017 to July 2018 in our hospital.The results of LDH,FA,IL-6 and carotid ultrasound were collected for statistical analysis.Results The levels of serum LDH,FA and IL-6 in ACI group were(254.56±62.87)U/L,(7.63±4.13)ng/ml,(88.35±13.56)ng/L,the levels of serum LDH and IL-6 were higher than those in control group(P<0.05),the levels of serum FA were lower than those in control group(P<0.05),the incidence of plaque and carotid stenosis in ACI group was significantly higher than those in control group(P<0.05),and the incidence of carotid artery stenosis in ACI group was significantly higher than that in control group(P<0.05).The most common type of atherosclerotic plaque was heterogeneous echo plaque,the incidence of which was higher than that of the control group(P<0.05),and the incidence of low echo plaque was higher than that of the control group(P<0.05).Conclusion Compared with the control group,the serum levels of LDH,FA,and IL-6 were abnormal in the ACI group.Carotid artery ultrasonography showed carotid intima thickening,unevenness,reduced inner diameter,and plaque formation,indicating that the carotid artery was detected by ultrasound.The combination of performance characteristics combined with blood LDH,FA,IL-6 levels has a certain clinical value in the evaluation of the progression of acute cerebral infarction.