基于Delphi法的辅助生殖技术治疗低预后人群诊疗中国专家意见

Delphi method-based Chinese experts’opinions on diagnosis and treatment of assisted repro-ductive technology in low-prognosis patients

目的形成科学合理、规范实用的中国辅助生殖技术(ART)治疗低预后人群诊疗的专家意见。方法运用Delphi法对中国ART治疗低预后人群的诊断、发病原因、治疗目标和治疗方法进行专家调查,并结合前期文献检索结果,编制第一轮问卷,征集辅助生殖领域专家意见;回收专家反馈意见,对问卷条目进行分析及修改后进入第二轮意见征集环节,经过两轮专家调研,通过专家意见赞成水平、专家参与调查研究的积极程度对本次专家调研结果进行评估。结果第一轮问卷形成30个陈述,专家参与的积极程度为87.0%,专家认可度均达到70%以上。第二轮问卷为26条陈述,专家参与的积极程度为95.7%,专家认可度均达到70%以上,最终形成26条专家意见。结论博洛尼亚低反应标准在某些方面存在欠缺,新的POSEIDON标准在一定程度上优化了低预后分类。通过对低预后的分类、病因、诊断及治疗方法进行充分的阐述并给予推荐性意见,希望能为临床改善低预后人群的成功率提供帮助。

Objective To form scientific,rational,standardized and practical expert opinions on the diagnosis and treatment of assisted reproductive technology(ART)in the low-prognosis population in China.Methods The diagnosis,causes or etiology,treatment targets,and treatment methods of ART were investigated by the Delphi method.The first round of the questionnaire was made by searching the literature and soliciting expert opinions in the field of ART.Then,the feedback from experts was collected,and the statements of the questionnaire were analyzed and revised for the second round of consultation by experts.The results of this expert survey were evaluated by the level of consistency of expert opinion and the degree of expert participation.Results The response rate of experts in the first and second rounds was 87.0%and 95.7%,respectively.After two rounds,all statements reached the target of 70%consensus.Conclusion The enthusiasm of experts was high,and their opinions were representative.The suggestions of Chinese experts on the diagnosis and treatment of ART with low-prognosis patients were made by expert consultation in the ART field using the Delphi survey technique.