多囊卵巢综合征对子代发育影响的研究进展

Research progress on the effect of polycystic ovarian syndrome on the development of the offspring

多囊卵巢综合征(polycystic ovary syndrome,PCOS)是育龄期女性最常见的生殖内分泌疾病,其特征表现为稀发排卵、高雄激素血症、卵巢多囊样改变。近年来越来越多的研究证实,PCOS影响子代生长发育以及代谢、神经精神、生殖等系统的发育。现对国内外最新发表文献进行综述,研究PCOS对子代发育的影响,以期对PCOS的治疗和PCOS母婴的健康提供理论依据。

Polycystic ovary syndrome(PCOS)is the most common reproductive endocrine disorder in women of reproductive age.PCOS is characterized by the presence of oligoovulation or anovulation(OA),hyperandrogenism(HA)and polycystic ovary morphology.More and more studies show that PCOS affects the offspring’s development in growth,metabolic,nervous and reproductive system.This paper collects recent published papers to review the effect of PCOS on the offspring’s development and provide a theoretical basis for the treatment of PCOS.