放疗联合甲磺酸阿帕替尼治疗晚期胃癌的效果分析

Analysis of the effect of radiotherapy combined with apatinib mesylate ta blets in the treatment of advanced gastric cancer

目的:探讨用放疗联合甲磺酸阿帕替尼片治疗晚期胃癌的临床效果。方法:将2017年5月至2019年5月期间山西省长治市人民医院收治的60例晚期胃癌患者作为研究对象。将这60例患者分为对照组和观察组(30例/组)。对两组患者均进行放疗。在此基础上,为观察组患者使用甲磺酸阿帕替尼片进行治疗。然后,比较两组患者的治疗效果、不良反应的发生率、生活的质量及其1年后的生存率。结果:治疗后,与对照组患者相比,观察组患者肿瘤的控制率、1年后的生存率及其生活质量得到改善例数的占比均较高,P<0.05。两组患者不良反应的发生率相比,P>0.05。结论:用放疗联合甲磺酸阿帕替尼片治疗晚期胃癌的效果显著,可有效地改善患者的生活质量,提高其生存率。

Objective:To investigate the clinical effect of radiotherapy combined with apatinib mesylate tablets in the treatment of advanced gastric cancer.Methods:A total of 60 patients with advanced gastric cancer admitted to Changzhi People’s Hospital of Shanxi Province from May 2017 to May 2019 were st udied.The 60 patients were divided into control group and observation group(30 cases/group).Both groups were treated with radiotherapy.On this basis,the observation group was treated with apatinib mesylate tablets.Then,treatment outcomes,incidence of adverse events,quality of life,and 1-year survival were compared between the two groups.Results:After treatment,compared with the control group,the tumor control rate,1-year survival rate and the number of cases with improved quality of life in the observation group were all higher(P<0.05).The incidence of adverse reactions between the two groups was P>0.05.Conclusion:Radiotherapy combined with apatinib mesylate is effective in the treatment of advanced gastric cancer,which ca n effectively improve the quality of life and improve the survi val rate.