用布洛芬混悬液与对乙酰氨基酚混悬液对高热患儿进行治疗的效果对比

Comparison of the effects of ibuprofen suspension and acetaminophen suspe nsion in the treatment of children with high fever

目的:探讨用布洛芬混悬液和对乙酰氨基酚混悬液对高热患儿进行治疗的临床效果。方法:选择2018年3月至2019年3月期间四川省甘孜藏族自治州人民医院收治的62例高热患儿作为研究对象。将这62例患儿分为布洛芬组(n=31)和对乙酰氨基酚组(n=31)。为布洛芬组患儿使用布洛芬混悬液进行治疗,为对乙酰氨基酚组患儿使用对乙酰氨基酚混悬液进行治疗。然后,比较两组患儿不良反应的发生率及其在治疗前、治疗1 h时、治疗2 h时、治疗3 h时其体温的情况。结果:治疗后,与对乙酰氨基酚组患儿相比,布洛芬组患儿不良反应的发生率更低,差异有统计学意义(P<0.05)。治疗前,两组患儿的体温相比,差异无统计学意义(P>0.05,t=0.0794)。与对乙酰氨基酚组患儿相比,布洛芬组患儿在治疗1 h时、治疗后2 h时及治疗3 h时其体温均更低,差异有统计学意义(P<0.05)。结论:与使用对乙酰氨基酚混悬液相比,使用布洛芬混悬液对高热患儿进行治疗的临床效果更好,其不良反应的发生率更低。

Objective:To investigate the clinical effect of ibuprofen suspension and acetaminophen suspension in the treatment of children with high fever.Methods:62 children with high fever admitted to The People’s Hospital of Ganzi Tibetan Autonomous Prefecture,Sichuan Province from March 2018 to March 2019 were selected as study subjects.The 62 children were divided into ibuprofen group(n=31)and acetaminophen group(n=31).Ibuprofen suspension was used for the children in the ibuprofen group and acetaminophen suspension was used for the children in the acetaminophen group.Then,the incidence of adverse reactions and their body temperature before,at 1 h,2 h,and 3 h of treatment were compared between the two groups.Results:After treatment,the incidence of adverse reactions was lower in the ibuprofen group than in the acetaminophen group,and the difference was statistically significant(P<0.05).Before treatment,there was no statistically significant difference in body temperature between the two groups(P>0.05,t=0.0794).Compared with the acetaminophen group,children in the ibuprofen group had lower body temperature at 1 h,2 h after treatment,and 3 h after treatment,with statistically significant differences(P<0.05).Conclusion:Compared with acetaminophen suspension,ibuprofen suspension has a better clinical effect and a lower incidence o f adverse reactions in children with high fever.