癌症患者症状群管理效果的Meta分析

Effect of symptom cluster management in cancer survivors: a meta-analysis

目的系统评价症状群管理干预对癌症患者症状群严重程度及日常生活干扰程度的影响。方法计算机检索多个中英文数据库,收集关于症状群管理干预对癌症患者症状群影响的临床随机对照试验,检索时间范围设定为各数据库建库至2019年5月。采用RevMan5.3软件进行数据分析。结果最终对8篇文献进行Meta分析,结果显示,症状群管理干预组在干预结束后症状群的严重程度[SMD=-0.42,95%CI(-0.54,-0.30)]和症状群对日常生活的干扰程度[SMD=-0.62,95%CI(-1.15,-0.09)]的改善情况均显著优于对照组。结论采用症状群管理干预,有利于减轻癌症患者症状群严重程度及对日常生活的干扰程度。

Objective To systematically evaluate the effect of symptom cluster management on symptom cluster severity and interfe-rence in daily life in cancer survivors.Methods Randomized controlled trials(RCTs)reporting the effect of management interventions on symptom clusters in cancer survivors were retrieved in electronic databases from inception to May,2019.RevMan5.3 was used for statistical analysis.Results Eight RCTs were included for analysis.The improvements in symptom cluster severity[SMD=-0.42,95%CI(-0.54,-0.30)]and interference in daily life[SMD=-0.62,95%CI(-1.15,-0.09)]in the intervention group were significantly better compared with the control group.Conclusion Symptom cluster management could effectively alleviate symptom cluster severity and interference in daily life in cancer patients.