妊娠期糖尿病血糖水平与不良妊娠结局的关系研究

Study on the relationship between the blood glucose level and the adverse pregnancy outcome of gestational diabetes mellitus

目的:研究妊娠期糖尿病血糖水平与不良妊娠结局的关系。方法:2018年1月-2019年1月收治妊娠期糖尿病患者300例作为A组,另选择同期体检的健康孕妇100例作为B组,比较两组妊娠结局。结果:A组空腹血糖及餐后2 h血糖水平均高于B组,早产、胎儿窘迫、产后出血及胎膜早破发生率均高于B组,差异有统计学意义(P<0.05)。空腹血糖及餐后2 h血糖水平与早产、胎儿窘迫、产后出血、胎膜早破发生率呈现正相关性,差异有统计学意义(P<0.05)。结论:妊娠期糖尿病患者空腹血糖、餐后2 h血糖水平较高,同时会增加不良妊娠结局发生率,应受到临床重点关注,积极控制血糖水平,防止不良妊娠结局产生,保障母婴安全。

Objective:To explore the relationship between the blood glucose level and the adverse pregnancy outcome of gestational diabetes mellitus.Methods:From January 2018 to January 2019,300 patients with gestational diabetes were selected as group A.Another 100 healthy pregnant women were selected as group B.We compared the pregnancy outcomes of the two groups.Results:In group A,fasting blood glucose and 2 hours postprandial blood glucose were higher than those in group B,and the incidence of premature delivery,fetal distress,postpartum hemorrhage and premature rupture of membranes were higher than those in group B,the difference was statistically significant(P<0.05).Fasting blood glucose and 2 hours postprandial blood glucose were positively correlated with the incidence of premature delivery,fetal distress,postpartum hemorrhage and premature rupture of membranes,the difference was statistically significant(P<0.05).Conclusion:The fasting blood glucose and 2-hour postprandial blood glucose levels of gestational diabetes are higher,at the same time,it will increase the incidence of adverse pregnancy outcomes,which should be paid more attention to in clinical practice,we should actively control blood glucose level,prevent adverse pregnancy outcomes,and ensure the safety of mothers and infants.