某院门诊妊娠患者用药分析

Prescriptions for Pregnant Outpatients

目的回顾性研究某院门诊妊娠患者用药情况,为药师完善药物咨询资料、开展妊娠药物咨询门诊提供帮助。方法抽取2018年6月某院产科分娩的患者,统计分析患者从末次月经至入院分娩前的门诊用药情况。结果共抽取279名妊娠患者,合计968张门诊处方,涉及药品156种。处方频次较高的药品为维生素及矿物类药(37.0%)、抗贫血药(20.7%)及中成药(10.7%)。超说明书用药处方99张(10.2%)。24种涉及药品的说明书中标明妊娠期禁忌使用,14种为不合理用药。结论药师需完善妊娠期常用药、常见病患者用药宣教单、中成药妊娠期安全性数据查询表、超说明书用药循证评价及妊娠期用药处方专项点评等资料,以促进安全合理用药。

Objective To investigate the prescriptions for pregnant outpatients in order to provide information for pharmacists to improve drug consultation data and standardize the drug consultation for pregnant women. Methods Patients who delivered in June 2018 were selected, whose use of drugs between the last menstrual period and the pre-hospital delivery was analyzed. Results Totally 279 pregnant outpatients were selected involving 968 prescriptions and 156 types of drugs. The main types of drugs used were vitamin and mineral drugs(37.0%), anaemic drugs(20.7%) and traditional Chinese medicine(10.7%). There were 99 off-label prescriptions(10.2%). Twenty-four types of drugs were contraindications during pregnancy in the labels, fourteen of which were prescribed without good reasons. Conclusion Pharmacists need to improve the instructions on medicines commonly used during pregnancy or for patients with common diseases, safety data sheets of Chinese patent medicines during pregnancy, evidence-based evaluation of off-label drugs and specific comments on medication prescriptions during pregnancy in order to ensure safe and rational medication.