31P-MRS扫描序列选择及进展

Selection and progresses of 31 P-MRS scanning sequences

人体许多组织中的含磷化合物可提供有关疾病微环境变化的重要信息。磷磁共振波谱(31 P-MRS)是研究人体不同组织的能量代谢和生化改变的无创性方法,可用于诊断疾病和监测治疗反应。磷的磁旋比低,在体含量相对较低,故31 P-MRS信噪比低;针对不同目的适当选择扫描序列可提高31 P-MRS质量。本文针对31 P-MRS不同扫描序列及其特点进行综述。

Phosphorus compounds exist in the tissue of human body,providing important information about microenvironment changes of diseases.Phosphorus magnetic resonance spectroscopy(31 P-MRS)is a non-invasive method to observe energy metabolism and biochemical changes of human tissue,which can be utilized in diagnosing disease and monitoring response to therapy.However,the magnetogyric ratio of phosphorus is low,and the in vivo content is relatively low,resulting low signal-to-noise ratio of phosphorus spectrum.It is very important to choose suitable scanning sequence to improve the quality.The characteristics,advantages and disadvantages of sequences used in 31 P-MRS were reviewed this article.