急性梗阻性化脓性胆管炎诊疗的研究进展

Progress in the diagnosis and treatment of acute obstructive suppurative cholangitis

急性梗阻性化脓性胆管炎(acute obstructive suppurative cholangitis,AOSC)是外科常见的急腹症,胆道结石和胆道梗阻是其主要的发病原因。本病起病急,进展快,病死率高。目前依靠临床表现、影像学检查及实验室检查不难做出诊断。在明确诊断的基础上,积极的非手术治疗及外科干预是治疗关键。本研究通过检索国内外相关文献,对AOSC的病因、诊断、治疗等方面的最新研究进展进行综述,并着重对内镜治疗的发展及手术时机进行论述,以便于服务于临床,为AOSC的规范化诊疗提供参考。

Acute obstructive suppurative cholangitis(AOSC)is a common acute abdomen in surgery.Cholelithiasis and bile duct obstruction are the main causes.The disease has the advantages of rapid onset,rapid progress and high mortality.At present,it is not difficult to make diagnosis by clinical manifestation,imaging examination and laboratory examination.On the basis of definite diagnosis,active non-surgical treatment and surgical intervention are the key.By searching the relevant literature on acute obstructive suppurative cholangitis at home and abroad,we reviews the latest research progress in etiology,diagnosis and treatment of AOSC,and focuses on the development of endoscopic treatment and the timing of operation,in order to serve the clinic and provide reference for the standardized diagnosis and treatment of AOSC.