张晓梅从湿浊瘀结论治原发性气管支气管淀粉样变

Experience of ZHANG Xiao-mei in the treatment of primary tracheobronchial amyloidosis from the accumulation of dampness,turbidity and blood stasis

原发性气管支气管淀粉样变是一种罕见的临床呼吸系统疾病,本病治疗难度大且易复发。西医目前缺乏统一的最佳方案,治疗手段主要有全身药物治疗、支气管镜下介入治疗、手术切除以及对症治疗等。张晓梅教授在辨证治疗原发性气管支气管淀粉样变的过程中,认为本病的基本病机为湿浊瘀结,先天或外邪因素损伤肺脏导致肺气不利,湿浊和瘀血相互搏结,形成淀粉样物质沉积于气道而发病,治疗当以宣气驱湿化浊,活血散结为主,临证灵活加减用药,获得了满意的效果,值得临床借鉴。

Primary tracheobronchial amyloidosis is a rare clinical respiratory disease.The treatment of this disease is difficult and easy to recur.At present,western medicine is lack of the best unified plan.The main treatment methods are drug therapy,bronchoscopic interventional therapy,surgical resection and symptomatic treatment.Professor ZHANG Xiao-mei thinks that the basic pathogenesis of this disease is dampness,turbidity and blood stasis.The congenital or external pathogenic factors damage the lung and effect the movement of lung qi.The dampness,turbidity and blood stasis combine with each other to form the deposition of starch like substances in the airway.The treatment should be mainly to promote lung qi to drive away the dampness and turbidity,and to promote blood circulation.The clinical treatment should be flexible to add and subtract drugs.This method of treatment has achieved satisfactory results and is worthy of clinical reference.