孕中期唐氏综合征血清学筛查预测不良妊娠结局的价值分析

Analysis of the Value of Serological Screening for Down’s Syndrome in the Second Trimester of Pregnancy in Predicting Adverse Pregnancy Outcomes

目的:探析孕中期唐氏综合征血清学筛查预测不良妊娠结局的价值。方法:将2017年6月-2018年12月于笔者所在医院接受唐氏血清筛查的826例孕妇作为研究对象,均接受唐氏血清筛查,并根据筛查结果,将其分为低风险组(757例)及高风险组(69例)。比较两组唐氏综合征发生情况及不良妊娠结局。结果:高风险组唐氏综合征发生率为5.79%,高于低风险组的0,差异有统计学意义(P<0.05)。高风险组自然流产、死胎及胎盘早剥发生率均显著高于低风险组,差异有统计学意义(P<0.05)。结论:唐氏血清筛查高风险与不良妊娠结局的发生具有一定的联系,可将其视为不良妊娠结局预测的一大指标。

Objective:To explore the value of serological screening for Down’s syndrome in the second trimester of pregnancy in predicting adverse pregnancy outcomes.Method:A total of 826 pregnant women who received Down’s serum screening in our hospital from June 2017 to December 2018 were selected as the research objects,all of whom received Down’s serum screening.According to the screening results,they were divided into the low-risk group(757 cases)and high-risk group(69 cases).The incidence of Down’s syndrome and adverse pregnancy outcomes of the two groups were compared.Result:The incidence of Down’s syndrome in the high-risk group was 5.79%,which was higher than 0 in the low-risk group,and the difference was statistically significant(P<0.05).The incidence of spontaneous abortion,stillbirth and placental abruption in the high-risk group were significantly higher than those in the low-risk group,and the difference was statistically significant(P<0.05).Conclusion:The high risk of Down’s serum screening is associated with the occurrence of adverse pregnancy outcomes,which can be regarded as a major index for the prediction of adverse pregnancy outcomes.