左氧氟沙星与头孢呋辛治疗肺炎的药物经济学分析

Pharmacoeconomic Analysis of Levofloxacin and Cefuroxime in the Treatment of Pneumonia

目的:探究左氧氟沙星与头孢呋辛治疗肺炎的药物经济学分析。方法:按照随机数字排序将所选取的肺炎患者分组,左氧氟沙星组(LE组)和头孢呋辛组(CA组),每组150例。通过分析LE组和CA组患者治疗效果、继发效应、成本-效果差异性来探究左氧氟沙星与头孢呋辛治疗肺炎患者的药物经济学分析。结果:治疗后,两组患者治疗效果相比较,差异无统计学意义(P>0.05)。治疗后,两组患者继发效应发生情况相比较,差异无统计学意义(P>0.05)。在有效率相同的情况下,LE组患者每增加1%,所需治疗费用就增加(22.69±5.35)元,CA组需增加(26.23±4.83)元。结论:左氧氟沙星与头孢呋辛对肺炎患者均有一定的治疗效果,但前者治疗所需成本较低。

Objective:To explore the pharmacoeconomic analysis of Levofloxacin and Cefuroxime in the treatment of pneumonia.Method:The selected patients with pneumonia were sorted according to random numbers,Levofloxacin group(LE group)and Cefuroxime group(CA group),150 cases in each group.The pharmacoeconomic analysis of Levofloxacin and Cefuroxime in the treatment of patients with pneumonia was explored by analyzing the differences in treatment effects,secondary effects,and cost-effectiveness analysis of patients in the LE and CA groups.Result:After treatment,the effects of the two groups were not significantly different(P>0.05).After treatment,the incidence of secondary effects in the two groups were similar(P>0.05).With the same effective rate,for every 1%increase in the LE group,the required treatment cost increased by(22.69±5.35)yuan,CA group increased by(26.23±4.83)yuan.Conclusion:Both levofloxacin and cefuroxime have a certain therapeutic effect on patients with pneumonia,but the cost of the former is relatively low.