瘢痕癌性溃疡诊断与治疗专家共识(2020年版)

Expert consensus on diagnosis and treatment of Marjolin ulcer(2020 version)

瘢痕癌,又被称为马氏溃疡,往往是在瘢痕溃疡的基础上恶变而成,其临床表现为溃疡长期不能愈合。瘢痕癌的致病因素与发生机制尚不十分清楚,但瘢痕反复破溃、糜烂、合并感染等慢性刺激在其病理发展中具有重要意义。目前,有关瘢痕癌的诊疗方案尚未形成统一认识。本文以国内外文献为基础,以全国相关领域专家的临床经验与观点为主要依据,在瘢痕癌性溃疡的病因、病理、临床表现、诊断与鉴别诊断、预防和治疗等方面汇集形成专家共识,为瘢痕癌性溃疡的防治提供参考。

Scar carcinoma,also named as Marjolin ulcer,is commonly derived from the malignant transformation of scar ulcer with its non-healing as the main clinic manifestation.Although the factors and mechanisms of scar carcinoma are not very clear,chronic stimulations such as repeated rupture,erosion and infection of scars play an important role in its pathogenesis.Currently,no consensus on the diagnosis and treatment of scar carcinoma has been developed.Based on the literature and the clinical experience and viewpoints of experts,we developed a consensus regarding on the etiology,pathology,clinical manifestation,diagnosis,prevention and treatment of scar carcinoma,so as to provide helpful reference for its prevention and treatment in clinic.