不同麻醉方式对行颈-胸-腹部三切口食管癌根治术患者术后肺部感染及炎性因子水平的影响

Effect of Different Anaesthesia Methods on Pulmonary Infection and Inflammatory Factor Level in Patients Undergoing Cervical-chest-abdominal Three-incision Radical Resection of Esophageal Carcinoma

目的:探究不同麻醉方式对行三切口(颈-胸-腹部)食管癌根治术患者术后肺部感染及其炎性因子水平的影响。方法:选取笔者所在医院2017年7月-2019年5月收治的行颈-胸-腹部三切口食管癌根治术的患者(94例)为试验对象,依照不同的麻醉方法,将入选患者分为两组,其中对照组(47例)行七氟烷麻醉,观察组(47例)行丙泊酚麻醉。观察两组的麻醉效果、术后肺部感染发生率及麻醉前后的炎性因子水平变化。结果:观察组的总有效率为93.62%,显著高于对照组,IL-8、IL-10及肺部感染发生率显著低于对照组,差异有统计学意义(P<0.05)。结论:采用丙泊酚对行三切口食管癌根治术患者具有较好的麻醉效果,可进一步降低术后肺部感染发生率,有效抑制炎症因子的释放,安全可靠。

Objective:To investigate the effect of different anesthetic methods on pulmonary infection and inflammatory factors in patients undergoing three-incision(cervical-chest-abdominal)radical resection of esophageal carcinoma.Method:From July 2017 to May 2019,94 patients undergoing radical resection of cervical,chest and abdominal esophageal carcinoma were selected as experimental subjects.According to different anaesthesia methods,the patients were divided into two groups,the control group(47 cases)was anesthetized with Sevoflurane and the observation group(47 cases)was anesthetized with Propofol.The anesthetic effect,the incidence of postoperative pulmonary infection and the level of inflammatory factors before and after anesthesia were observed.Result:The total effective rate of the observation group was 93.62%,which was significantly higher than that of the control group,the level of IL-8,IL-10 and incidence pulmonary infection in the observation group was significantly lower than that in the control group(P<0.05).Conclusion:The use of Propofol has better anesthesia effect on the patients undergoing radical operation of the three-incision esophageal cancer,and can further reduce the incidence of postoperative pulmonary infection,effectively inhibit the release of the inflammatory factors,and is safe and reliable.