骨折内固定术后感染的药物治疗

Drug therapy for infection after internal fixation of fracture

骨折内固定术后感染是创伤骨科治疗中的难题,复发率高、疗程长、治疗费用高。随着医疗技术的发展,临床上对骨折内固定术后感染的治疗方法也有较大发展,改良的Ilizarov法、Papineau法、Masquelet技术在各自的研究领域均证明有较好的疗效。而随着抗生素骨水泥的广泛应用,骨科临床医师对于抗感染药物在骨折内固定术后感染中的需求也越发迫切。笔者对骨折内固定术后感染的诊断、病原学分布及术后感染的药物治疗进行综述,为临床治疗骨折内固定术后感染提供参考。

Infection after fracture internal fixation is a clinical problem in trauma orthopedics.The high recurrence rate,long course of treatment and high treatment cost are the main features of the disease.With the development of medical technology,clinical treatment methods for postoperative infection after internal fixation of fractures have also been greatly developed.The improved Ilizarov method,Papineau method and Masquelet technique have been proved to be effective in their respective research fields.With the wide application of antibiotic bone cement,orthopedic clinicians have an increasingly urgent need for anti-infective drugs in postoperative infection after internal fixation of fractures.The authors review the diagnosis,pathogenic distribution and drug treatment of infection after fracture internal fixation,which provides a reference for the clinical treatment of postoperative infection following fracture internal fixation.