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补中益气丸联合地屈孕酮片治疗习惯性流产临床研究 被引量:7

Clinical Study on Buzhong Yiqi Pills Combined with Dydrogesterone Tablets for Habitual Abortion
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摘要 目的:观察补中益气丸联合地屈孕酮片治疗习惯性流产的临床效果。方法:选取116例习惯性流产患者为研究对象,随机分观察组与对照组各58例,对照组给予口服地屈孕酮片治疗,观察组给予补中益气丸联合地屈孕酮片治疗。比较2组免疫功能指标、性激素水平、总有效率及足月分娩率。结果:治疗后,2组白细胞介素-4(IL-4)、孕激素、雌激素水平均升高(P<0.05),2组干扰素-γ(IFN-γ)、IFN-γ/IL-4均下降(P<0.05)。观察组IL-4、孕激素、雌激素水平均高于对照组(P<0.05),IFN-γ、IFN-γ/IL-4均低于对照组(P<0.05)。观察组总有效率、足月分娩率均高于对照组,差异有统计学意义(P<0.05)。结论:补中益气丸联合地屈孕酮片治疗习惯性流产效果显著,能改善患者的免疫功能及性激素水平,提高足月分娩率。 Objective:To observe the clinical effect of Buzhong Yiqi pills combined with dydrogesterone tablets for habitual abortion.Methods:A total of 116 cases of patients with habitual abortion were selected as the study subjects and randomly divided into the control group and the observation group,58 cases in each group.The control group was orally given dydrogesterone tablets,and the observation group was additionally treated with Buzhong Yiqi pills based on the treatment of the control group.The indexes of immune function,levels of sex hormones,total effective rates and term delivery rates in the two groups were compared.Results:After treatment,the levels of IL-4,progesterone and estrogen in the two groups were increased(P<0.05),and the levels in the observation group were higher than those in the control group(P<0.05);the indexes of IFN-γand IFN-γ/IL-4 in the two groups were decreased(P<0.05),and the indexes in the observation group were lower than those in the control group(P<0.05).The total effective rate and term delivery rate in the observation group were higher than those in the control group,the difference being significant(P<0.05).Conclusion:The therapy of Buzhong Yiqi pills combined with dydrogesterone tablets has significant curative effect in treating habitual abortion,which can improve immune function,levels of sex hormones and term delivery rates.
作者 曹晓波 董虹华 毛晓红 CAO Xiaobo;DONG Honghua;MAO Xiaohong
出处 《新中医》 CAS 2020年第13期49-51,共3页 New Chinese Medicine
关键词 习惯性流产 补中益气丸 地屈孕酮片 免疫功能 性激素 足月分娩率 Habitual abortion Buzhong Yiqi pills Dydrogesterone tablets Immune function Sex hormones Term delivery rate
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