接骨七厘片联合骨肽注射液治疗肱骨骨折临床研究

Clinical Study on Jiegu Qili Tablets Combined with Bone Peptide Injection for Humeral Fracture

目的:观察接骨七厘片联合骨肽注射液治疗肱骨骨折的治疗效果。方法:选取60例肱骨骨折患者,通过随机分组法分为对照组和研究组,每组30例。2组均行外科手术固定复位后,对照组采用单纯骨肽注射液治疗,研究组采用接骨七厘片联合骨肽注射液治疗,15 d为1个疗程,治疗2个疗程后比较2组临床疗效。结果:研究组总有效率为90.00%,对照组总有效率为60.00%,研究组总有效率明显高于对照组(P<0.05)。治疗前,2组骨代谢指标比较,差异无统计学意义(P>0.05)。治疗后,研究组骨钙素、骨碱性磷酸酶、Ⅰ型胶原羧基端肽β特殊序列(β-CTX)明显高于对照组(P<0.05)。研究组各类型骨折愈合时间均明显短于对照组(P<0.05)。结论:接骨七厘片联合骨肽注射液治疗肱骨骨折临床疗效较好,可以有效促进肱骨骨折愈合,改善患者临床症状。

Objective:To observe the curative effect of Jiegu Qili tablets combined with bone peptide injection for humeral fracture.Methods:A total of 60 cases of patients with humeral fracture were selected and randomly divided into the control group and the study group,30 cases in each group.After fixation and reduction by surgery,the control group was simply treated with bone peptide injection,and the study group was additionally treated with Jiegu Qili tablets based on the treatment of the control group.After two courses of treatment,with 15 days as a course,the clinical effect in the two groups was compared.Results:The total effective rate was 90.00%in the study group,significantly higher than that of 60.00%in the control group(P<0.05).Before treatment,there was no significant difference being found in the comparison of bone metabolic markers between the two groups(P>0.05).After treatment,the indexes of osteocalcin,bone alkaline phosphatase andβC-terminal telopeptides of typeⅠcollagen(β-CTX)in the study group were significantly higher than those in the control group(P<0.05).The healing time of all types of fractures in the study group was significantly shorter than that in the control group(P<0.05).Conclusion:The therapy of Jiegu Qili tablets combined with bone peptide injection has good clinical effect in treating humeral fracture,which can promote fracture healing and improve clinical symptoms of patients.