3例肝硬化患者非O1/非O139群霍乱弧菌感染的病例报道

A case report of three cases of non-O1/non-O139 Vibrio cholerae infection in patients with cirrhosis

霍乱是由霍乱弧菌引起的烈性肠道传染病,典型临床表现为急性起病,剧烈腹泻、呕吐以及由此引起的脱水、肌肉痉挛,严重者导致循环衰竭和急性肾衰竭。肝硬化患者感染霍乱弧菌报道少见,本文回顾性分析了3例肝硬化患者感染非O1/非O139群霍乱弧菌流行病学特点、发病特点、临床表现、治疗及转归,肝硬化患者出现发热、腹泻等症状时,需重视血培养与大便培养。

Objective Cholera is a potent intestinal infectious disease caused by Vibrio cholerae. Its typical clinical manifestations are acute onset, severe diarrhea and vomiting, and consequent dehydration, muscle spasm, severe circulatory failure and acute renal failure. Reports of Vibrio cholerae infection in patients with cirrhosis are rare. This article retrospectively reviewed the epidemiological characteristics, pathogenesis, clinical manifestations, treatment and outcomes of 3 cases of patients with cirrhosis infected by non-O1/non-O139 Vibrio cholera. When symptoms such as fever and diarrhea were observed in patients with cirrhosis, clinicians should pay attention to blood culture and stool culture.