抗生素与漱口液在预防糖尿病患者种植牙术后感染的临床对比研究

A clinical comparative study of antibiotics and mouthwash in prevention of postoperative infection after dental implants in patients with diabetes mellitus

目的探讨口服奥硝唑片和含漱洗必泰漱口液在预防糖尿病患者种植牙术后感染的临床效果对比,为糖尿病患者种植牙术后抗炎提供用药指导。方法选择2016年8月—2018年7月于本院口腔种植科收治的伴有糖尿病的患者60例作为研究对象,随机数表法分为抗生素组和含漱组两组,每组各30例。分别于患者种植牙术后应用抗生素和漱口液进行术后抗炎治疗,对术后第3天进行疼痛评价,术后第7日评价患者创口愈合情况及创口感染情况。结果两组患者在术后疼痛,伤后愈合情况,创口感染情况三个方面相比,差异均无统计学意义(P>0.05)。结论对于糖尿病患者种植牙术后应用抗生素和漱口液可以取得同样的临床疗效,但抗生素存在一定副作用,故推荐使用漱口液。

Objective Compare the clinical effect of oral ornidazole tablets and rinsed chlorhexidine gargle on the prevention of postoperative infection in diabetic patients those received dental implants,and provide clinical medication guidance for those patients.Methods 60 patients admitted to stomatology department of the first affiliated hospital of Bengbu Medical Collage from August 2016 to July 2018,complicated with diabetes mellitus,were selected as study subjects.The patients were divided into antibiotic group and gargle group according to random number table method,each group has 30 patients.Antibiotics and mouthwash were used to treat the patients after dental implant,respectively.Postoperative pain was evaluated on the 3rd day after surgery,and wound healing and infection were evaluated on the 7th day after surgery.Results There was no significant difference between the two groups in three aspects:postoperative pain,wound healing and bacterial stick index analysis(P>0.05).Conclusions The same clinical effect could be achieved by using antibiotics and mouthwash in diabetic patients after dental implants.However,antibiotics have some side effects,so it is recommended to use mouthwash.