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恶性萎缩性丘疹病一例 被引量:2

Malignant atrophic papulosis:a case report
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摘要 患者,女,58岁。躯干四肢散在红斑丘疹4个月余。皮肤科检查:躯干四肢散在红斑丘疹,丘疹中央可见瓷白色萎缩性斑片,边缘隆起伴红晕,伴腹痛。皮损组织病理示:表皮萎缩变薄,真皮浅中层胶原变性,血管周围散在小片状的淋巴细胞及组织细胞浸润。诊断:恶性萎缩性丘疹病。给予阿司匹林、双嘧达莫、雷贝拉唑钠、美沙拉嗪、阿嗪米特口服治疗1个月后腹痛症状缓解,全身皮疹颜色变淡。2个月后患者腹痛加重诊断为肠穿孔,术后无明显改善。4个月后去世。 A 58-year-old female presented with scattered erythema and papules on her trunk and limbs with abdominal pain for more than 4 months.Dermatologic examination showed scattered erythema and papules on her trunk and limbs,with porcelain white atrophic patches in the center of the papules which was surrounded by pink edematous border.Biopsy showed the epidermis atrophy and the denatured collagen in the superficial layer of the dermis and the vascular layer was surrounded by lymphocytes and histiocytes.The diagnosis of malignant atrophic papulosis was made.The abdominal pain and the lesions were improved after treated with aspirin,dipyridamole,rabeprazole sodium,mesalazine,azinemide for 1 month.After 2 months the abdominal pain aggravated again and the diagnosis of enterobrosis was made and the patient was treated with laparoscopic surgery with no significant improvement.The patient was died from enterobrosis after 4 months.
作者 黎松 王娟 杨希川 游弋 LI Song;WANG Juan;YANG Xichuan;YOU Yi(Department of Dermatology,Southwest Hospital,Army Military Medical University,Chongqing 400038,China)
出处 《中国麻风皮肤病杂志》 2020年第8期493-494,496,共3页 China Journal of Leprosy and Skin Diseases
基金 西南医院临床研究基金(编号:SWH2016JSTSYB-29)。
关键词 恶性萎缩性丘疹病 Kohlmeier-Degos综合征 malignant atrophic papulosis Kohlmeier-Degos syndrome
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