摘要
最近研究表明表观遗传机制在基因表达调控中具有重要作用,包括DNA甲基化、染色质修饰和重塑、非编码RNA的多种活性以及RNA甲基化。本文综述了RNA相关表观遗传学在黑素瘤中的研究进展。
Recent studies have revealed epigenetics plays an important role in the regulation of gene expression,including DNA methylation,chromatin modification and remodeling,multiple activities of non-coding RNA,and RNA methylation.The update of RNA-related epigenetics of melanomas is reviewed in this paper.
作者
乐张慧
王焱
方方
孙建方
YUE Zhanghui;WANG Yan;FANG Fang;SUN Jianfang(Department of Pathology,Institute of Dermatology,Chinese Academy of Medical Science&Peking Union Medical College,Nanjing 210042,China;Department of Surgery,Institute of Dermatology,Chinese Academy of Medical Science&Peking Union Medical College,Nanjing 210042,China)
出处
《中国麻风皮肤病杂志》
2020年第8期509-512,共4页
China Journal of Leprosy and Skin Diseases
基金
国家自然科学基金面上项目(编号:81872216)
中国医学科学院医学与健康科技创新工程(编号:CIFMS-2017-I2M-1-017)。
