99例腹型过敏性紫癜患儿激素使用情况回顾性分析

Retrospective Analysis on Use of Hormones in 99 Children with Abdominal Henoch-Sch?nlein Purpura

目的:通过对北京儿童医院99例腹型过敏性紫癜患儿激素使用情况进行回顾性分析,探讨激素使用现状并提出下一步研究问题和方案。方法:提取病例信息,结合临床实际,对99例患儿的激素品种选择、初始日剂量、初始使用时间、激素的减量情况共四项指标及其可能影响因素进行描述及统计分析。结果:99例患儿初始激素品种选择一致,初始使用剂量、初始给药时间、激素减量后的品种选择、减量幅度以及每次减量后的使用时间均不统一。结论:目前腹型过敏性紫癜患儿激素的应用现状混乱,缺乏统一循证指导,对提出的问题假设拟进行后续分阶段研究。

Objective: To retrospectively analyze the use of hormones in 99 children with abdominal Henoch-Sch?nlein purpura in Beijing Children’s Hospital,and to probe into the current status of the use of hormones,so as to further put forward the research issues and schemes. Methods: The general information of 99 cases was extracted. Combined with the clinical practice,the selection of hormone varieties,initial daily dose,initial administration time and hormone reduction of 99 children were presented by descriptive analysis.Results: The initial hormonal varieties of 99 children were consistent. The initial dosage,initial administration time,variety selection after hormone reduction,reduction range,and administration time after each reduction were not unified. Conclusion: At present,the current status of the use of hormones in children with abdominal Henoch-Sch?nlein purpura is chaotic and there is a lack of unified evidence-based guidance. The hypothesis of the proposed problems is planned to be followed up in stages.