“四位一体”营养管理模式对鼻咽癌放疗患者营养状态及张口功能的影响

Influence of Four-in-one Nutrition Management Model on Nutrition Status and Mouth Opening Function of Nasopharyngeal Carcinoma Patients Undergoing Radiotherapy

目的:探讨“四位一体”营养管理模式对鼻咽癌放疗患者营养状态及张口功能的影响。方法:将2018年2月1日~2019年12月1日收治的86例鼻咽癌放疗患者,按照营养干预方案不同分为对照组和观察组各43例,对照组给予常规营养干预,观察组在此基础上给予“四位一体”营养管理模式;比较干预前后两组营养状况、急性放射反应、免疫功能、生活质量[采用健康调查简表(SF-36)]。结果:干预后,观察组营养状况、免疫功能及SF-36评分均优于对照组(P<0.01);干预6周后,观察组急性放射反应评分低于对照组(P<0.05,P<0.01)。结论:将“四位一体”营养管理模式应用于鼻咽癌放疗患者中,可有效改善患者营养状态及张口功能情况,减轻对免疫功能的损伤,从而增强疗效,提高生活质量。

Objective:To explore the effect of four in one nutritional management model on the nutritional status and mouth opening function of nasopharyngeal carcinoma patients undergoing radiotherapy.Methods:From February 1,2018 to December 1,2019,86 patients with nasopharyngeal carcinoma treated by radiotherapy were divided into control group and observation group according to different nutrition intervention schemes with 43 patients in each group.The control group was given conventional nutrition intervention,and the observation group was given four-in-one nutrition management model on this basis.Nutritional status,acute radiation response score,immune function,and quality of life score were compared between the two groups before and after the intervention[(the MOS item short form health survey(SF-36)was used].Results:Nutritional status,immune function and SF-36 score in the observation group were better than those in the control group(P<0.01).After 6 weeks of intervention,the acute radiation response score of the observation group was lower than that of the control group(P<0.05,P<0.01).Conclusion:The application of four in one nutritional management model in patients with nasopharyngeal cancer undergoing radiotherapy can effectively improve the nutritional status and mouth opening function of patients,reduce the damage to immune function,and thus enhance the curative effect and improve the quality of life.