摘要
MicroRNA(miRNA)是一种内源性的非编码单链小分子RNA,它是通过与靶基因3'UTR区结合来调控靶基因的表达。miRNA在红细胞生命代谢过程中发挥重要作用,本文意在对miRNA参与调节红系生长发育、增殖、分化及凋亡的机制进行综述。
MicroRNA(miRNA)is endogenously small non-coding regulatory RNA which plays important roles in many critical processes.It regulates gene expression through binding to the untranslated region of target mRNA.MicroRNA acts as a vital part in erythropoiesis.In this review,we mean to summarize the state of knowledge on the role of miRNAs in the regulation of different stages of erythropoiesis.
作者
赵星云
卞茂红
ZHAO Xing-yun;BIAN Mao-hong(The First Affiliated Hospital of Anhui Medical University,Anhui 230022)
出处
《临床输血与检验》
CAS
2020年第4期445-448,共4页
Journal of Clinical Transfusion and Laboratory Medicine