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胰高血糖素样肽-1受体激动剂对2型糖尿病患者心血管获益的潜在机制 被引量:8

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摘要 2型糖尿病(T2DM)患者往往容易并发心血管疾病,其主要表现为动脉粥样硬化性疾病。糖尿病的严重程度、糖尿病继发引起的代谢变化及血管损伤均是T2DM患者发生心血管疾病的风险因素。近年的研究发现新型降糖药物胰高血糖素样肽-1受体激动剂(GLP-1RA)如利拉鲁肽及艾塞那肽等,可以明显减少T2DM患者心血管疾病的发生。本文就GLP-1RA的作用及其对T2DM患者心血管获益的潜在机制作一综述。
出处 《浙江医学》 CAS 2020年第14期1563-1565,共3页 Zhejiang Medical Journal
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