血管内支架介入成形术对老年缺血性脑血管病患者的神经功能、动脉血流速度及预后的影响

The Effect of Endovascular Stent Angioplasty on Neurological Function,Arterial Blood Flow Velocity and Prognosis in Elderly Patients with Ischemic Cerebrovascular Disease

目的:探讨血管内支架介入成形术对老年缺血性脑血管病(ICVD)患者的神经功能、动脉血流速度及预后的影响。方法:选取2018年3月~2019年4月期间我院收治的117例老年ICVD患者作为研究对象,根据随机数字表法分为对照组(n=58)和研究组(n=59),其中对照组患者予以保守药物治疗,研究组患者予以血管内支架介入成形术治疗,比较两组患者疗效、神经功能、动脉血流速度、预后及并发症情况。结果:研究组治疗6个月后的临床总有效率为91.53%(54/59),高于对照组的72.41%(42/58)(P<0.05)。两组患者治疗后1个月、治疗后3个月、治疗后6个月美国国立卫生研究院卒中量表(NIHSS)评分均下降(P<0.05),且研究组低于对照组(P<0.05)。两组患者治疗后6个月大脑中动脉、基底动脉、颈内动脉血流速度均升高(P<0.05),且研究组高于对照组(P<0.05)。两组患者治疗后1个月、治疗后3个月、治疗后6个月改良Rankin量表(m RS)评分呈下降趋势(P<0.05),且研究组低于对照组(P<0.05)。两组患者并发症发生率对比未见统计学差异(x^2=2.261,P=0.133)。结论:老年ICVD患者经血管内支架介入成形术治疗后的疗效显著,可有效改善患者神经功能、动脉血流速度及预后,且不增加并发症发生率,具有较高的临床应用价值。

Objective: To investigate the effect of endovascular stent angioplasty on the neurological function, arterial blood flow velocity and prognosis in elderly patients with ischemic cerebrovascular disease(ICVD). Methods: 117 elderly patients with ICVD who were admitted to our hospital from March 2018 to April 2019 were selected as the study objects, they were divided into control group(n=58) and study group(n=59) according to the method of random number table. The patients in the control group were treated with conservative drugs. The patients in the study group were treated with intravascular stent angioplasty. The efficacy, neurological function,arterial blood flow velocity, prognosis and complications of the two groups were compared. Results: The total clinical effective rate of the study group at 6 months after treatment was 91.53%(54/59), which was higher than 72.41%(42/58) of the control group(P<0.05). The scores of National Institutes of Health Stroke Scale(NIHSS) in the two groups decreased at 1 month after treatment, 3 months after treatment and 6 months after treatment(P<0.05), the scores in the study group were lower than those in the control group(P<0.05). The blood flow velocity of the middle cerebral artery, the basilar artery and the internal carotid artery in the two groups increased at 6 months after treatment(P<0.05), and those in the study group were higher than those in the control group(P<0.05). The modified Rankin scale(m RS) scores of the two groups showed a decreasing trend at 1 month after treatment, 3 months after treatment, 6 months after treatment(P<0.05), and that in the study group was higher than that in the control group(P<0.05). There was no significant difference in the incidence of complications between the two groups(x^2=2.261, P=0.133). Conclusion: After the treatment of intravascular stent angioplasty, the curative effect of old patients with ICVD is significant, which can effectively improve the nerve function, arterial blood flow velocity and prognosis of patients, it does not increase the incidence of complications, it has high clinical application value.