摘要
由严重急性呼吸综合征冠状病毒-2(severe acute respiratory syndrome coronavirus 2,SARS-CoV-2)引起的新型冠状病毒肺炎(coronavirus disease-2019,COVID-19)已经发展为全球大流行性疾病,给人类带来了巨大的危机与灾难.该病主要经呼吸道飞沫和密切接触传播,但是否能够经消化道感染与传播一直是医学界和广大公众非常关注的问题.本述评从COVID-19的临床表现与消化系统症状、病毒的检测与分离培养、宿主细胞受体血管紧张素转化酶2的表达与分布等方面,对该问题进行了论述与分析.SARS-CoV-2存在经消化道感染与传播的潜在风险,应加强进一步的确证研究与有效防控.
Coronavirus disease-2019(COVID-19)caused by severe acute respiratory syndrome coronavirus 2(SARSCoV-2)has evolved into a global pandemic and brought great crises and disasters to mankind.The disease is transmitted mainly through respiratory droplets and close contact,but whether it can be transmitted through the digestive tract and by faeces has been a problem of great concern to the medical community and the general public.This review discusses and analyzes the problem in terms of clinical manifestations and digestive system symptoms of COVID-19,detection and isolation of virus,expression and distribution of angiotensin-converting enzyme 2 receptor,etc.There is a potential risk of infection and transmission of SARS-CoV-2 through the digestive tract.It is suggested to carry out further confirmatory research and strengthen effective means of prevention and control.
作者
刘纯杰
Chun-Jie Liu(Institute of Biotechnology,Academy of Military Medical Sciences,Beijing 100071,China)
出处
《世界华人消化杂志》
CAS
2020年第14期563-569,共7页
World Chinese Journal of Digestology
基金
“艾滋病和病毒性肝炎等重大传染病防治”科技重大专项资助项目,No.2018ZX10101003-005-005.
