肝硬化患者肝外肿瘤的发病风险及治疗措施

Risk and treatment of non-hepatic cancers in patients with cirrhosis

肝硬化患者是肝癌的高危人群,然而,肝硬化患者是否也存在更高的肝外肿瘤风险仍存争议.此外,肝硬化患者肝功能不全常常限制了肝外肿瘤的外科手术和抗癌药物治疗的应用,这使得肝硬化患者肝外肿瘤的治疗也面临着巨大挑战.这篇述评旨在简要回顾肝硬化患者肝外肿瘤的发病风险及治疗策略.

Patients with cirrhosis are at a high risk for hepatocellular carcinoma.However,it remains controversial about whether or not there is a high risk for non-hepatic cancers in patients with liver cirrhosis.Additionally,the management of non-hepatic cancers in cirrhotic patients is a clinical challenge,because the use of surgery and anticancer drugs is often compromised by the presence of liver dysfunction.This editorial aims to briefly summarize the findings on the risk and management of non-hepatic cancers in patients with cirrhosis.