基于CT血管成像的血流储备分数对肺癌的诊断价值

Diagnostic Values of Blood Flow Reserve Fraction Based on CT Angiography for Lung Cancer

目的:探讨基于CT血管成像的血流储备分数对肺癌淋巴结转移的诊断价值。方法:2018年1月到11月选择在本院进行诊治的肺癌患者60例,所有患者都给予常规CT检查与CT血管成像,记录成像特征与相关血流储备分数-血流量(blood flow,BF)、血容量(blood volume,BV)、平均通过时间(mean transit time,MTT),判断诊断价值。结果:在60例患者中,病理确诊为淋巴结转移20例,非淋巴结转移40例。转移组的毛刺征、分叶征、棘突征、空泡征等CT征象发生率显著高于非转移组(P<0.05)。转移组的肺动脉BF、BV值显著低于非转移组(P<0.05),MTT值显著高于非转移组(P<0.05)。在60例患者中,Spearman相关分析显示淋巴结转移与MTT成显著正相关性(P<0.05),与BF、BV值成显著负相关性(P<0.05)。结论:CT血管成像在肺癌中的应用能反映患者的血流储备分数状况,有利于判断患者的淋巴结转移情况,有很好的应用价值。

Objective:To investigate the diagnostic values of blood flow reserve fraction based on CT angiography for lymph node metastasis of lung cancer.Methods:From January to November 2018,60 patients with lung cancer who were treated in our hospital were selected.All patients were underwent routine CT and CT angiography.The imaging characteristics and associated blood flow reserve scores-blood flow(BF)blood volume(BV),mean transit time(MTT)were recorded,and were to determine the diagnostic value.Results:Of the 60 patients,20 were diagnosed with lymph node metastasis and 40 with non-lymph node metastasis.The incidence of CT signs such as burr sign,lobulated sign,spinous process sign and vacuole sign in the metastatic group were significantly higher than that in the non-metastasis group(P<0.05).The BF and BV values of pulmonary artery in the metastatic group were significantly lower than those in the non-metastasis group(P<0.05),and the MTT value were significantly higher than that in the non-metastasis group(P<0.05).In 60 patients,Spearman correlation analysis showed a significant positive correlation between lymph node metastasis and MTT(P<0.05),and a significant negative correlation with BF and BV values(P<0.05).Conclusion:The application of CT angiography in lung cancer can reflect the patient's blood flow reserve score,which is helpful for judging the lymph node metastasis of patients,and has good application value.