基于脑血流的功能成像技术在缺血性脑卒中诊疗中的研究进展

Advances in the study of functional imaging based on cerebral blood flow in the diagnosis and treatment of ischemic stroke

近年来,人脑功能的探索一直是神经科学领域研究热点之一,随着人脑连接组学的提出,多模态的神经成像技术,将逐渐成为研究人类全脑神经网络功能的重要突破口。解剖学角度上神经元与血管相伴而行的特征提示脑血流可作为反映神经功能的可靠信号。本文将以此为切入点,综述基于脑内血流的脑功能成像技术的研究进展,以及神经元和伴行血管互作的模式对于以缺血性脑卒中为代表的脑血管系统疾病的价值所在。

In recent years,the exploration of human brain function has been one of the research hotspots in the field of neuroscience.With the proposal of Human Connectome,the multimodal neuroimaging technology gradually becomes an important breakthrough in the study of human whole brain neural network function.From the anatomical point of view,the characteristics of neurons accompanied by blood vessels suggest that cerebral blood flow can be used as a reliable signal to reflect neurological function.Taking this as a starting point,this paper reviews the scientific progress of brain functional imaging based on intracerebral blood flow,and the significance of the interaction between neurons and concomitant vessels in cerebrovascular diseases in the case of ischemic stroke.