摘要
经典名方是近年来的研究热点之一。国家相关政策指引下的古代经典名方复方制剂的开发有其历史必然性,其关键是在中医药理论指导下细化古今临证应用实际并标准化,用于大生产工艺设计。通过经典名方形成路径分析与内涵解析,概述了经典名方在中医药理论体系中的重要地位,明确了组成与制法固定的药用物质是经典名方开发的核心内涵。在此基础上,对经典名方的筛选、古方今病适用性及标准化出路等经典名方开发所面临的宏观问题进行了探讨,还就目前的政策形势与研究现状,阐明了经典名方的研发价值。
The famous classical formulas(FCF),which occupy the most important position in the prescription theory,had been brought out following the progress of traditional Chinese medicine(TCM). Its formation and exploitation,essentially the ingredient constitution and preparation technology,is an objective trend of TCM. The development of related product under the guidance of relevant national policies has its historical inevitability,as the development of formula granules in recent decades had laid a solid foundation for it. The key to exploit these FCF is to refine and standardize the clinical applications through the ages with the guidance of TCM theory,for the process design of massive industrial production. As a result of the analysis of its definition and connotation,it is clear that the core connotation of FCF is the medicinal substances with fixed formula compatibility and stable preparation process. Furthermore,the screening strategy,the exploitation value,and the applicability between ancient prescriptions and nowadays diseases,had also been discussed based on the current policy situation and research status.
作者
张鹏
刘安
邬兰
宋宗华
陈士林
ZHANG Peng;LIU An;WU Lan;SONG Zong-hua;CHEN Shi-lin(Chinese Pharmacopoeia Commission,Beijing 100061,China;Instiute of Chinese Materia Medica,China Academy of Chinese Medical Sciences,Beijing 100700,China;School of Chinese Materia Medica,Beijing University of Chinese Medicine,Beijing 102488,China)
出处
《中国实验方剂学杂志》
CAS
CSCD
北大核心
2020年第15期183-194,共12页
Chinese Journal of Experimental Traditional Medical Formulae
基金
国家“重大新药创制”科技重大专项(2019ZX09731002)
中国中医科学院“十三五”重点领域研究专项(ZZ10-007)。
关键词
经典名方
方剂理论
复方制剂
产品开发
标准化
工艺设计
质量控制
famous classical formulas
formula theory
compound preparation
product development
standardization
process design
quality control